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Эксперты «упаковали» наночастицы серебра с антимикробным действием в защитную оболочку, которая не вредит клеткам. Антибактериальный препарат на основе наночастиц серебра – достижение ученых нескольких... Нетоксичный антибиотик нового поколения изобрели российские и корейские ученые

Эксперты «упаковали» наночастицы серебра с антимикробным действием в защитную оболочку, которая не вредит клеткам.

Антибактериальный препарат на основе наночастиц серебра – достижение ученых нескольких российских вузов и южнокорейского Университета Данкук, сообщает пресс-служба НИТУ «МИСиС». Результаты исследования опубликовал научный журнал Nanomaterials.

Применение наночастиц серебра в биомедицине считается ограниченным из-за их токсичности: наносеребро провоцирует окислительный стресс в живых клетках. Решили эту проблему путем модификации поверхности наночастиц – сделали ее из соединений с нулевой или низкой токсичностью.

Затем ученые оценили степень токсичность лекарства по его действию на желудочно-кишечный тракт мышей. Оказалось, при дозировках менее 4 мг/кг после однократного воздействия отсутствуют значимые энтеро- и гепатотоксические эффекты.

Модифицировав поверхность серебряных наночастиц, эксперты существенно улучшили их биосовместимость. Это значит, минимизировали риск развития устойчивости болезнетворных микроорганизмов к материалам на основе серебра.

Ученые продолжают свою работу по получению получения новых антибиотиков широкого спектра действия, которые не вызовут привыкание.

Источник: https://news.yellmed.ru/

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